Hepatitis G Viruses (HGV): A Study on Prevalence, Transmission, and Co-Infection

Abstract

Hepatitis virus infection is an increasing severe life-threating complication that gradually damages the liver. Hepatitis G is identified as a blood-borne pathogen that can cause various problems in human body. The hepatitis G virus (HGV) is also known as GB virus C (GBV-C) that is a newly described human virus of member of the Flaviviridae family and is similar genome organization as hepatitis C virus (HCV), and may be a cause of chronic liver disease. Some investigations have demanded that it is not associated with any known disease, but may be a cause of co-infection with HBV, HCV and HIV infection. The HGV is widespread around the world that has been ascertained to influence course and prognosis in the HIV-infected patient. It has been detected in patients with idiopathic fulminant hepatic failure (FHF) and hepatocellular carcinoma. It can be transmitted by blood transfusion, volunteer blood donors, and other parenteral processes. At present very little information is available about hepatitis G virus (HGV) infection and pathogenesis. This study tries to discuss the virology, symptoms, transmission, and co-infection of the HGV.