Liver Cirrhosis: Causes, Severity, and Management Strategy

Abstract

The liver is the largest internal organ of the body. It is a vital organ that performs various important physiological functions of the body. It is a unique organ that has the ability to regenerate itself. Liver cirrhosis is the end-stage of chronic liver disease (CLD) that is characterized by organ failures, increased levels of systemic inflammation and high short-term mortality. It is an awfully heterogeneous condition of the liver that spreads from an early asymptomatic to an advanced stage with various complications that continuously damages the liver and its functions. Some common causes of liver cirrhosis are over alcohol use, non-alcoholic fatty liver disease, hepatitis virus infections, with many patients having overlapping causes. These patients have experience of muscle cramps, pruritus, poor-quality sleep, and sexual dysfunction. Liver transplantation is the only life-saving option for cirrhosis patients. This study tries to discuss the causes, complications, severity, and management techniques of this fatal disease.