Journal of Innovations in Medical Research https://www.paradigmpress.org/jimr <p><a href="https://www.paradigmpress.org/jimr/about"> <img src="https://www.paradigmpress.org/public/site/images/admin/journal-of-innovations-in-medical-research-2ca3d18d256e866b25821bc0eaa26bb1.jpg" /> </a></p> en-US office@paradigmpress.org (London Office) submission@paradigmpress.org (Hong Kong Office) Thu, 30 Oct 2025 07:28:55 +0000 OJS 3.3.1.0 http://blogs.law.harvard.edu/tech/rss 60 Management of Acute and Chronic Hepatitis B and C Viral Infections https://www.paradigmpress.org/jimr/article/view/1820 <p>Hepatitis is an inflammation of the liver that can be caused by over alcohol and toxin chemical consumption, some medications, and viruses, such as hepatitis B, C, D, and E. The hepatitis B virus (HBV) and hepatitis C virus (HCV) can develop acute and chronic viral infections that are major causes of liver cirrhosis, liver cancer, liver transplantation, and liver related death worldwide. Both of these two viruses can transmit through the vertical or horizontal route, such as blood or body fluids from an infected person, unprotected sex with an infected person, sharing needles with infected person, and from infected mother to baby during birth. Symptoms of both diseases are similar, and some common symptoms are jaundice, loss of appetite, fever, fatigue, dark urine, joint pain, abdominal pain, diarrhea, nausea, and vomiting, etc. The incubation period is 8-20 weeks for hepatitis B, and 2-6 weeks for hepatitis C. At present there are two vaccines of HBV, but no vaccine available for HCV.</p> Haradhan Kumar Mohajan Copyright (c) 2025 https://www.paradigmpress.org/jimr/article/view/1820 Thu, 30 Oct 2025 00:00:00 +0000 Research on Miniaturization and Low-Power Technology of Portable Ventilators in Home Medical Scenarios https://www.paradigmpress.org/jimr/article/view/1821 <p>This study achieved dual breakthroughs of <strong>≤</strong>15 W average power consumption and 8.2 h medium-pressure endurance under extreme geometric constraints of 9.8 L and 2.8 kg, through an integrated architecture of “modular-graphene-micro-fan” and a full-chain low-power model of “brushless motor + intelligent frequency conversion + sleep-wake.” National-level testing showed noise levels of 33 dB, pressure output deviation of ±0.3 cmH₂O, and leak compensation of 185 L min⁻¹. A 50-case, 30-day multicenter home clinical validation indicated a 1.7 mmHg decrease in morning PaCO₂ (non-inferiority achieved), no statistically significant difference in AHI compared to controls, average daily use of 7.9 h, device satisfaction of 90%, and compliance of 96%, with only 5 cases of Grade I adverse events. The results first confirmed that portable ventilators with <strong>≤10 L</strong> can achieve equivalent therapeutic outcomes to traditional devices in real-world settings, providing a registrable and industrializable technical paradigm for home respiratory support under the silver economy.</p> Yinglong Jiang Copyright (c) 2025 https://www.paradigmpress.org/jimr/article/view/1821 Thu, 30 Oct 2025 00:00:00 +0000