Management Strategies of Fatal Liver Infection Due to Hepatitis C Virus (HCV)

Abstract

Hepatitis is a liver inflammatory disease that can cause severe liver scarring. Hepatitis C is a blood-borne fatal disease of the liver that is caused by a virus called the hepatitis virus C (HCV), which lives in liver tissue and blood. It can be both an acute (short-term) illness (25-15%) and a chronic (long-term) infection (75-85%) that may gradually damage the liver. It is characterized by possible development of both liver and extra-hepatic disorders. The HCV infection is usually asymptomatic. Chronic infection with the HCV represents a major health problem worldwide that accounts for life-threatening liver disease, such as liver cirrhosis, hepatocellular carcinoma (HCC), liver failure, and ultimately needs liver transplantation, or to face unexpected premature death. Early treatment for hepatitis C is highly cost-effective and disease progression restricted, and can be avoided end-stage liver disease. The aim of this study is to identify the risk factors, transformation rout, and complication of HCV for the management of the disease to save millions of lives.