Analysis of the New Progress in the Treatment of Parkinson’s Disease from the Perspective of Antioxidant

Abstract

Parkinson’s disease (PD) is currently the second most common neurodegenerative disease. The pathological features of PD are degeneration of dopaminergic neurons in the brain, which leads to motor retardation, rigidity, quiescence, tremor, postural instability, smell disorders, pain, sleep disorders, depression and other non-motor symptoms Although the etiology of PD is still not fully understood, the occurrence of oxidative stress has been closely related to the pathogenesis of PD for a long time However, as there are many side effects of known PD treatment drugs, and there is a lack of effective treatment means to control the disease by inhibiting oxidative stress pathway, controlling the progression of PD disease by inhibiting oxidative stress has become a new direction of modification therapy. At present, a large number of studies have focused on the process of inhibiting oxidative stress. In this paper, a brief review of previous studies was made to provide new clinical ideas for the treatment of PD.