Advances in the Study of the Pathogenesis of Post-Stroke Depression

Abstract

Poststroke depression is a common psychiatric disease among stroke patients, can lead to higher disability and mortality rates in stroke patients, and there is a bidirectional relationship between stroke and depression (Medeiros, G.C., et al., 2020). Stroke increases the risk of PSD, and depression is an independent risk factor for stroke. Due to the high prevalence of depression, which seriously affects normal life, it is very necessary to effectively treat and prevent the occurrence of PSD. This paper will discuss the pathogenesis of post-stroke depression from both biological and social psychological perspectives. Only when the mechanism is clear, can more specific targeted therapy be carried out.